ETERMIS

The dermal filler for everyone

  • The range consists of three monophasic, cohesive, hyaluronic acid (HA) fillers combined with mannitol.
  • Mannitol is an antioxidant that acts as a free-radical scavenger to minimise degradation of HA.1
  • ETERMIS product range offers what you need to achieve beautiful results in the treatment of fine lines, moderate and severe wrinkles.2


Quality standards of German engineering

Excellent safety profile

ETERMIS product range meets high expectations:

  • good tolerability3
  • low rate of adverse events4

High-tech meets aesthetics

ETERMIS fillers are designed for:

  • long-lasting duration of aesthetic effect5
  • low extrusion force7

Broad filler range. High performance.

ETERMIS product range is ideal for the aesthetic treatment2 of

  • delicate areas and lips, e.g. increase of lip volume (ETERMIS 3, 4)
  • fine lines (ETERMIS 2) and moderate wrinkles (ETERMIS 3)
  • deep and severe folds (ETERMIS 4)

A specific, patented6 product composition.

  1. Mendoza G et al., 2007; Belda JI et al., 2005.
  2. See Instructions for Use for each formulation.
  3. Turlier V et al., 2010.
  4. 0.02% incident rate, according to internal data 2011.
  5. Results may vary, depending on patient’s age, gender, skin quality, lifestyle, injection area, etc. The expected duration is twelve month for ETERMIS 3.
  6. Patent application no WO2008/068297 (applies for ETERMIS 2/3/4)
  7. Kim et al. A randomized, evaluator-blinded, split face comparison study of the efficacy and safety of a novel mannitol containing monophasic hyluronic acid dermal filler for the treatment of moderate to severe nasolabial folds, Ann Dermatol, Vol 28. No 3, 2016

  • Product profile

    ETERMIS 2 – when it comes to delicate areas

    Your reliable partner for mild and superficial wrinkles

    • perioral lines
    • lips (contours)

    Injection protocol:
    Inject into the upper dermis with an angle of approximately 15 degrees between needle and skin surface.1

    ETERMIS 3 – create impressing aesthetic results

    The art of effective treatments – for moderate wrinkles and lip enhancement

    • nasolabial folds
    • marionette lines
    • lip enhancement

    Injection protocol:
    Inject into the mid to deep dermis with an angle of approximately 30–35 degrees between needle and skin surface.1

    ETERMIS 4 – strong but discreet results

    Deep and severe wrinkles:

    • nasolabial folds
    • marionette lines
    • lip enhancement

    Injection protocol:
    Inject into the mid and deep dermis with an angle of approximately 30–35 degrees between needle and skin surface.1

    1. See Merz Aesthetics Guidelines for injection technique.

    Indications for Etermis 2, Etermis 3 and Etermis 4 are subject to the Instructions for Use (last revision 03/2016)

  • Treatment Areas

    Satisfying results with ETERMIS 2

    Female, perioral

    Female, perioral

    Predictable results with ETERMIS 3

    Male, nasolabial folds

    Female, marionette lines and nasolabial folds

    Natural looking results with ETERMIS 4

    Female, lips

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