Lift & Contour with long-term collagen stimulation

Healthy young skin contains collagen that gives it volume, flexibility and strength. As part of the ageing process, the skin's natural collagen breaks down resulting in the loss of facial volume. This loss of elasticity and volume results in wrinkles, facial lines, and skin laxity that rob the skin of its youthful appearance. RADIESSE® stimulates the skin’s production of collagen to restore volume in the skin, smooth away wrinkles and improve skin quality in the long-term.

RADIESSE® is now also available with integral 0.3% lidocaine (RADIESSE® Lidocaine). The line extension product combines the proven efficacy and safety of RADIESSE® with extra treatment comfort.

  • Product Profile

    RADIESSE® – instant volume lifting and contouring

    RADIESSE® is an injectable dermal filler that temporarily adds volume to help smooth moderate to severe facial wrinkles and gives an immediate lifting and firming effect of the skin. Once injected, RADIESSE® directly provides volume and lift needed to diminish the signs of ageing because of the calcium-based microspheres and gel that comprise the product. Both the gel and the microspheres are completely broken down by the body over time.

    RADIESSE® – a collagen stimulator 1,2,3

    The unique formulation of RADIESSE® stimulates the production of new collagen, which results in increased volume that may last a year or more in many patients*. Thanks to this method of wrinkle correction, RADIESSE® is more and more becoming the favourite injectable filler of many patients and medical professionals.

    * Individual results are dependent on age, skin type, indications, lifestyle, metabolism and, of course, the area treated.

    Enhanced patient satisfaction 1,2,3,4

    With just one syringe, many patients obtain an immediate and long-lasting youthful appearance. A RADIESSE® treatment is simple, quick, comfortable and convenient and provides immediately visible results that last.

    RADIESSE® offers

    • Immediate correction of moderate to severe wrinkles
    • Immediate lifting and contouring effects
    • Stimulates the production of the skin's natural collagen*
    • Long-term improvement of skin quality*
    • Feels soft and looks natural
    • Provides results that last a year or more in many patients*
    • Allows for an easy and convenient treatment

    * Individual results are dependent on age, skin type, indications, lifestyle, metabolism and, of course, the area treated.

    1) Bass LS, et al. Calcium hydroxylapatite (RADIESSE®) for treatment of nasolabial folds: long-term safety and efficacy results. Aesthet Surg J. 2010 Mar; 30(2): p235-238.
    2) Moers-Carpi MM, Opi Tufet J. Calcium Hydroxylapatite versus Nonanimal Stabilized Hyaluronic Acid for the Correction of Nasolabial Folds: a 12-Month, Multicenter, Prospective, Randomized, Controlled, Split-Face Trial. Dermatol Surg. 2008; 34: p210-215.
    3) Tzikas TL. A 52-Month Summary of Results Using Calcium Hydroxylapatite for Facial Soft Tissue Augmentation. Dermatol Surg. 2008 Jun; 34 Suppl 1: p9-15.
    4) Yutskovkaya Y. et al., A Randomized, Split-Face, Histomorphologic Study Comparing a Volumetric Calcium Hydroxylapatite and a Hyaluronic Acid-Based Dermal Filler, J Drugs Dermatol. 2014; 13(9):1047-1052

  • Mode of Action

    RADIESSE® – how it works1,2,3

    Once injected, RADIESSE® provides immediate volume and correction but also continues to work by stimulating the skin to produce its own natural collagen. Over time, the gel is absorbed and the body metabolizes the CaHA-microspheres, leaving behind only the skin's natural collagen.

    1. Effect

    Once injected, RADIESSE® shows an immediate one-to-one correction and lifting effect. It can instantly soften your smile lines, replace lost volume in your cheeks, or contour your jawline.

    RADIESSE® Lidocaine significantly reduces pain during treatment and throughout the first hour after treatment.4

    2. Effect

    Over the following weeks, RADIESSE® microspheres stimulate the skin to produce new collagen for a soft, natural look.

    Collagen net

    Newly formed collagen surrounds the microspheres. The microspheres are eventually metabolised by the body's normal processes.

    3. Effect

    The new collagen provides a long-term effect that may last for a year or more in many patients.*

    * Individual results are dependent on age, skin type, indications, lifestyle, metabolism and, of course, the area treated.
    1) Marmur ES, et al. J Cosmet Laser Ther. 2004;6:223-226
    2) Berlin AL, et al. Dermatol Surg. 2008;34:S64-S67.
    3) Yutskovskaya Y, et al. J Drugs Dermatol. 2014; 13 (9): 1047-1052
    4) Daniel Schachter. Pain Control Using the Injectable Dermal Filler Calcium Hydroxylapatite with Integral Lidocaine for the Correction of Nasolabial Folds. Poster # 1810. E-POSTER PRESENTATION Saturday, 3/21/2015 from 12:15:00 PM to 12:20:00 PM.

  • Treatment Areas

    * RADIESSE® may be used to correct excessive volume deficits that occur due to age-related volume loss of the hands. RADIESSE® is the first and only US FDA approved dermal filler for hands.

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RADIESSE® - The Lifting Filler

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